Study proposals

SubjectSubmitterSiteStatus
1Effectiveness of ECT and its clinical predictors in the NetherlandsDore LoefAUMC/GGZ inGeestPublished in Molecular Psychiatry in October 2024
2Cognitive safety of ECT and its clinical predictors in the NetherlandsDore LoefAUMC/GGZ inGeestPublished in Journal of Affective Disorders in January 2024
3Sensitivity of the MMSE in detecting cognitive side-effects induced by ECTDore LoefAUMC/GGZ inGeestPublished in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging in August 2024
4Predicting the outcome of ECT with the DM-TRD staging model for therapy resistance MDDJordy RoversRadboudumcPublished in Acta Psychiatrica Scandinavica in March 2023
5Inflammation markers, BMI, and smoking as predictors of response to ECT in depressionDominika KaraszweskaAUMCApproved on 5/9/22
6Pretreatment cognitive functioning in severely depressed patients indicated for ECTMana Fazel / Mike van KesselAUMCThis proposal has been withdrawn
7The predictive and mediating role of sleep in depression and cognitive dysfunction before and after ECTMana FazelAUMCThis proposal has been withdrawn
8Individual outcome prediction of ECT treatmentMetten SomersUMCUApproved on 5/9/22
9The relationship between stimulus pulse width and effectiveness of ECT in MDDJulia MeijerAUMC/GGZ inGeestApproved on 2/20/23
10The relationship between inflammation and the effectiveness of ECT in patients with psychotic depressionKara DrexlerAUMC/GGZ inGeestApproved on 2/20/23
11Symptom network structure and strength of depressive and cognitive symptoms following ECT treatment: a longitudinal network analysis studyMelissa ZandstraUMCUPublished in Brain Stimulation in March 2026 & published in Journal of Affective Disorders in September 2026
12ECT as a treatment for depressive symptom profiles in treatment resistant depressionTom BiemansRadboudumcApproved on 12/11/23
13Impact of frequency of pulses and train duration on seizure threshold, effectiveness, and side-effects of ECTPiotr JażdżykGGZ inGeestApproved on 12/11/23
14The effect of sex on ECT outcome and its clinical predictors in Major Depressive DisorderMachteld BlankenMUMCPublished in Journal of Affective Disorders in November 2026
15Model-based economic evaluation of the position of ECT vs pharmacotherapy in the Dutch depression treatment algorithmStijn PeetersTrimbos InstituteApproved on 4/15/24
16Effectiveness of electroconvulsive therapy comparing evidence from prospective clinical studies versus real worldRobin CobbenUMCUPublished in Comprehensive Psychiatry in June 2026
17Intranasal esketamine versus electroconvulsive therapy: a multicenter observational cohort studyPim van der MeerUMCUApproved on 10/14/24
18The role of comorbid autism spectrum disorder in the effectiveness of electroconvulsive therapy for major depressive disorderGijs StultiensRadboudumcApproved on 3/31/25
19Comparing neurocognitive effects of electroconvulsive therapy with and without lithium in patients with depressionLiese van den EyndeUMCUApproved on 6/16/25
20Prediction of electroconvulsive therapy response and remission in late-life
depression
Rahat MuslemRadboudumcApproved on 9/8/25
21Identifying the optimal electric field magnitude in electroconvulsive therapyJulia MeijerAUMC/GGZ inGeestApproved on 1/26/26
22The effect of structural measures of brain reserve on post-ECT cognitive declineOlivera Story-JovanovaRadboudumcApproved on 5/4/26
23The effect of clinical measures of cognitive reserve on post-ECT cognitive declineOlivera Story-JovanovaRadboudumcApproved on 5/4/26
24Right unilateral versus bitemporal ECT, a study on effectiveness and adverse eventsRaymond SaletGGZ CentraalApproved on 9/7/26
25ECT treatment course and clinical outcomes in young versus older adultsEliane de Mol van OtterlooAUMCApproved on 9/7/26

If you have access (send request to d.loef@ggzingeest.nl), you can view all research proposals via https://drive.google.com/drive/folders/1aDginAGB6jg-QUjdluowHUf4fDi2V6oF?usp=drive_link